Gene

kirrel1a

ID

ZDB-GENE-040426-2126

Name

kirre like nephrin family adhesion molecule 1a

Symbol

kirrel1a Nomenclature History

Previous Names

kirrel
kirrela
Neph1a (1)
zgc:64208 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Exhibits identical protein binding activity. Predicted to localize to integral component of membrane. Is expressed in several structures, including forebrain neural keel; forebrain neural rod; pectoral fin bud; ventral mesenchyme; and ventral mesoderm. Orthologous to human KIRREL1 (kirre like nephrin family adhesion molecule 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2008

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d820 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Charlton-Perkins et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kirrel1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nephrotic syndrome type 23	Alliance	Nephrotic syndrome, type 23	619201

Associated With kirrel1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Domain	IPR013162	CD80-like, immunoglobulin C2-set
Family	IPR051275	Cellular adhesion and signaling domain-containing protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily