Gene
tcirg1b
- ID
- ZDB-GENE-040426-2022
- Name
- T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
- Symbol
- tcirg1b Nomenclature History
- Previous Names
-
- wu:fb44e06
- wu:fi46h07
- zgc:55891
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in vacuolar acidification. Predicted to localize to plasma membrane and vacuolar proton-transporting V-type ATPase complex. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Is expressed in macrophage and yolk syncytial layer. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55891 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive osteopetrosis 1 | Alliance | Osteopetrosis, autosomal recessive 1 | 259700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ATPase, V0 complex, subunit 116kDa, eukaryotic | V-type ATPase, V0 complex, 116kDa subunit family |
|---|---|---|---|
|
UniProtKB:Q7ZVM7
|
822 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tcirg1b-201
(1)
|
Ensembl | 2,475 nt | ||
| mRNA |
tcirg1b-202
(1)
|
Ensembl | 523 nt | ||
| mRNA |
tcirg1b-204
(1)
|
Ensembl | 3,373 nt | ||
| ncRNA |
tcirg1b-002
(1)
|
Ensembl | 773 nt |
Interactions and Pathways
No data available
Plasmids
No data available