Gene
dpm3
- ID
- ZDB-GENE-040426-1782
- Name
- dolichyl-phosphate mannosyltransferase subunit 3, regulatory
- Symbol
- dpm3 Nomenclature History
- Previous Names
-
- zgc:73376 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to contribute to dolichyl-phosphate beta-D-mannosyltransferase activity. Involved in muscle structure development. Predicted to localize to dolichol-phosphate-mannose synthase complex and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation. Is expressed in brain; cloaca; pronephric duct; solid lens vesicle; and vertical myoseptum. Orthologous to human DPM3 (dolichyl-phosphate mannosyltransferase subunit 3, regulatory).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73376 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Marchese et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| muscular dystrophy-dystroglycanopathy type B15 | Alliance | ?Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type B, 15 | 618992 |
| Muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 15 | 612937 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR013174 | Dolichol-phosphate mannosyltransferase subunit 3 |
Domain Details Per Protein
| Protein | Length | Dolichol-phosphate mannosyltransferase subunit 3 |
|---|---|---|
|
UniProtKB:Q1LXA2
|
92 |
Interactions and Pathways
No data available
Plasmids
No data available