Gene
clu
- ID
- ZDB-GENE-040426-1774
- Name
- clusterin
- Symbol
- clu Nomenclature History
- Previous Names
-
- zgc:73352
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable misfolded protein binding activity. Acts upstream of or within regulation of neuron death. Predicted to be located in several cellular components, including chromaffin granule; endoplasmic reticulum; and mitochondrial membrane. Is expressed in several structures, including digestive system; male organism; nervous system; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; diabetic retinopathy; exfoliation syndrome; and muscular disease (multiple). Orthologous to human CLU (clusterin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Jeong et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Clusterin | Clusterin, C-terminal | Clusterin-like | Clusterin, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q6PBL3
|
448 |
Interactions and Pathways
No data available
Plasmids
No data available