Gene

rdh8b

ID

ZDB-GENE-040426-1759

Name

retinol dehydrogenase 8b

Symbol

rdh8b Nomenclature History

Previous Names

rdh8l
zf 1.3 (1)
zfprRDH1 (1)
zgc:73320

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable NAD-retinol dehydrogenase activity. Predicted to be involved in retinol metabolic process. Predicted to act upstream of or within estrogen biosynthetic process. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. Is expressed in brain; eye; fin; retina; and retinal photoreceptor layer. Orthologous to human RDH8 (retinol dehydrogenase 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73320 (2 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rdh8b Human Ortholog

No data available

Associated With rdh8b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020904	Short-chain dehydrogenase/reductase, conserved site
Family	IPR002347	Short-chain dehydrogenase/reductase SDR
Family	IPR011348	17beta-dehydrogenase
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily