Gene
cap2
- ID
- ZDB-GENE-040426-1758
- Name
- cyclase associated actin cytoskeleton regulatory protein 2
- Symbol
- cap2 Nomenclature History
- Previous Names
-
- zgc:113089
- zgc:73317
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity and adenylate cyclase binding activity. Predicted to be involved in cAMP-mediated signaling; cell morphogenesis; and regulation of adenylate cyclase activity. Predicted to act upstream of or within cytoskeleton organization. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in central nervous system; heart; male organism; muscle; and neural tube. Orthologous to human CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Effendi et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Effendi et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cardiomyopathy, dilated, 2I | 620462 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR013992 | Adenylate cyclase-associated CAP, N-terminal |
| Conserved_site | IPR018106 | CAP, conserved site, N-terminal |
| Conserved_site | IPR028417 | CAP, conserved site, C-terminal |
| Domain | IPR006599 | CARP motif |
| Domain | IPR013912 | Adenylate cyclase-associated CAP, C-terminal |
| Domain | IPR017901 | C-CAP/cofactor C-like domain |
| Domain | IPR053950 | CAP, N-terminal domain |
| Family | IPR001837 | Adenylate cyclase-associated CAP |
| Homologous_superfamily | IPR016098 | Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal |
| Homologous_superfamily | IPR036222 | Adenylate cyclase-associated CAP, N-terminal domain superfamily |
| Homologous_superfamily | IPR036223 | Adenylate cyclase-associated CAP, C-terminal superfamily |
Domain Details Per Protein
| Protein | Length | Adenylate cyclase-associated CAP | Adenylate cyclase-associated CAP, C-terminal | Adenylate cyclase-associated CAP, C-terminal superfamily | Adenylate cyclase-associated CAP, N-terminal | Adenylate cyclase-associated CAP, N-terminal domain superfamily | CAP, conserved site, C-terminal | CAP, conserved site, N-terminal | CAP, N-terminal domain | CARP motif | C-CAP/cofactor C-like domain | Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IXA9
|
468 | |||||||||||
|
UniProtKB:Q5BJ21
|
461 |
Interactions and Pathways
No data available
Plasmids
No data available