Gene

ilvbl

ID

ZDB-GENE-040426-1623

Name

ilvB (bacterial acetolactate synthase)-like

Symbol

ilvbl Nomenclature History

Previous Names

zgc:66376 (1)
zgc:85697 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable acetolactate synthase activity and flavin adenine dinucleotide binding activity. Acts upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of acetolactate synthase complex. Orthologous to human ILVBL (ilvB acetolactate synthase like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66376 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Fitzgerald et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ilvbl Human Ortholog

No data available

Associated With ilvbl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000399	TPP-binding enzyme, conserved site
Domain	IPR011766	Thiamine pyrophosphate enzyme, TPP-binding
Domain	IPR012000	Thiamine pyrophosphate enzyme, central domain
Domain	IPR012001	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
Family	IPR045229	Thiamine pyrophosphate enzyme
Homologous_superfamily	IPR029035	DHS-like NAD/FAD-binding domain superfamily
Homologous_superfamily	IPR029061	Thiamin diphosphate-binding fold

Domain Details Per Protein

Protein	Length	DHS-like NAD/FAD-binding domain superfamily	Thiamin diphosphate-binding fold	Thiamine pyrophosphate enzyme	Thiamine pyrophosphate enzyme, central domain	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain	Thiamine pyrophosphate enzyme, TPP-binding	TPP-binding enzyme, conserved site
UniProtKB:A0A8M9P109 InterPro	651
UniProtKB:Q6NV04 InterPro	621

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ilvbl-201 (1) Ensembl	Ensembl	3,327 nt	Select Tool ZFIN BLAST
mRNA	ilvbl-202 (1) Ensembl	Ensembl	957 nt	Select Tool ZFIN BLAST
mRNA	ilvbl-203 (1) Ensembl	Ensembl	5,250 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations