Gene
gmps
- ID
- ZDB-GENE-040426-1503
- Name
- guanine monophosphate synthase
- Symbol
- gmps Nomenclature History
- Previous Names
-
- cb632 (1)
- sb:cb632
- wu:fb76b01
- wu:fi05a09
- zgc:66002
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable GMP synthase activity. Predicted to be involved in GMP biosynthetic process. Predicted to act upstream of or within purine nucleotide biosynthetic process. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Orthologous to human GMPS (guanine monophosphate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb632 (16 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001674 | GMP synthase, C-terminal |
| Domain | IPR004739 | GMP synthase, glutamine amidotransferase |
| Domain | IPR017926 | Glutamine amidotransferase |
| Domain | IPR022310 | NAD/GMP synthase |
| Domain | IPR025777 | GMP synthetase ATP pyrophosphatase domain |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR029062 | Class I glutamine amidotransferase-like |
Domain Details Per Protein
| Protein | Length | Class I glutamine amidotransferase-like | Glutamine amidotransferase | GMP synthase, C-terminal | GMP synthase, glutamine amidotransferase | GMP synthetase ATP pyrophosphatase domain | NAD/GMP synthase | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B8JLW8
|
692 |
Interactions and Pathways
No data available
Plasmids
No data available