Gene
cacng2a
- ID
- ZDB-GENE-040426-1401
- Name
- calcium channel, voltage-dependent, gamma subunit 2a
- Symbol
- cacng2a Nomenclature History
- Previous Names
-
- cacng2
- zgc:64200 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have voltage-gated calcium channel activity. Involved in AMPA selective glutamate receptor signaling pathway. Predicted to localize to AMPA glutamate receptor complex and postsynaptic density membrane. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 10. Is expressed in brain and central nervous system. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64200 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Roy et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 10 | Alliance | ?Intellectual developmental disorder, autosomal dominant 10 | 614256 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PMP-22/EMP/MP20/Claudin | Voltage-dependent calcium channel, gamma-2 subunit | Voltage-dependent calcium channel gamma subunit | Voltage-dependent calcium channel, gamma subunit |
|---|---|---|---|---|---|
|
UniProtKB:Q6PFS3
|
324 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cacng2a-201
(1)
|
Ensembl | 2,994 nt |
Interactions and Pathways
No data available
Plasmids
No data available