Gene
rab7a
- ID
- ZDB-GENE-040426-1352
- Name
- RAB7a, member RAS oncogene family
- Symbol
- rab7a Nomenclature History
- Previous Names
-
- rab7 (1)
- zgc:64058
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within endosomal transport. Located in late endosome. Is expressed in neural crest and telencephalon. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150470 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 2B | Alliance | Charcot-Marie-Tooth disease, type 2B | 600882 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|
|
UniProtKB:Q7T2C6
|
207 |
Interactions and Pathways
No data available
Plasmids