Gene
cyp7a1
- ID
- ZDB-GENE-040426-1296
- Name
- cytochrome P450, family 7, subfamily A, polypeptide 1
- Symbol
- cyp7a1 Nomenclature History
- Previous Names
-
- cyp7a1
- cyp7a1a
- zgc:63920 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have steroid hydroxylase activity. Predicted to be involved in bile acid biosynthetic process and cholesterol homeostasis. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in basal plate midbrain region; central nervous system; otic vesicle; and retinal ganglion cell layer. Orthologous to human CYP7A1 (cytochrome P450 family 7 subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 15 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2450 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017972 | Cytochrome P450, conserved site |
Family | IPR001128 | Cytochrome P450 |
Family | IPR002403 | Cytochrome P450, E-class, group IV |
Family | IPR024204 | Cytochrome P450, cholesterol 7-alpha-monooxygenase-type |
Family | IPR030681 | Cholesterol 7-alpha-monooxygenase |
Family | IPR050529 | Cytochrome P450, sterol 14-alpha demethylase |
Homologous_superfamily | IPR036396 | Cytochrome P450 superfamily |
Domain Details Per Protein
Protein | Length | Cholesterol 7-alpha-monooxygenase | Cytochrome P450 | Cytochrome P450, cholesterol 7-alpha-monooxygenase-type | Cytochrome P450, conserved site | Cytochrome P450, E-class, group IV | Cytochrome P450, sterol 14-alpha demethylase | Cytochrome P450 superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:F1QU76
|
512 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
cyp7a1-201
(1)
|
Ensembl | 1,987 nt |
Interactions and Pathways
No data available
Plasmids
No data available