Gene

ddb1

ID
ZDB-GENE-040426-1272
Name
damage-specific DNA binding protein 1
Symbol
ddb1 Nomenclature History
Previous Names
  • zgc:63840
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have damaged DNA binding activity. Involved in negative regulation of apoptotic process and regulation of cell cycle process. Predicted to localize to cullin-RING ubiquitin ligase complex and nucleus. Is expressed in blastomere; endoderm; nervous system; pharyngeal arch; and somite. Orthologous to human DDB1 (damage specific DNA binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Hu et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ddb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
White-Kernohan syndrome 619426
Associated With ddb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminal
Domain IPR018846 Cleavage/polyadenylation specificity factor, A subunit, N-terminal
Family IPR050358 RSE1/DDB1/CFT1/CPSF1
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Domain Details Per Protein
Protein Length Cleavage/polyadenylation specificity factor, A subunit, C-terminal Cleavage/polyadenylation specificity factor, A subunit, N-terminal RSE1/DDB1/CFT1/CPSF1 WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q6PGT6 897
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ddb1-201 (1) Ensembl 3,429 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations