Gene
pgm1
- ID
- ZDB-GENE-040426-1245
- Name
- phosphoglucomutase 1
- Symbol
- pgm1 Nomenclature History
- Previous Names
-
- zgc:63718
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have phosphoglucomutase activity. Predicted to be involved in galactose catabolic process; glucose metabolic process; and glycogen biosynthetic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation It; endometrial cancer; and teratoma. Is expressed in central nervous system; digestive system; myotome; notochord; and yolk syncytial layer. Orthologous to human PGM1 (phosphoglucomutase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63718 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation It | Alliance | Congenital disorder of glycosylation, type It | 614921 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR016066 | Alpha-D-phosphohexomutase, conserved site |
| Domain | IPR005844 | Alpha-D-phosphohexomutase, alpha/beta/alpha domain I |
| Domain | IPR005845 | Alpha-D-phosphohexomutase, alpha/beta/alpha domain II |
| Domain | IPR005846 | Alpha-D-phosphohexomutase, alpha/beta/alpha domain III |
| Family | IPR005841 | Alpha-D-phosphohexomutase superfamily |
| Family | IPR045244 | Phosphoglucomutase |
| Homologous_superfamily | IPR016055 | Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III |
| Homologous_superfamily | IPR036900 | Alpha-D-phosphohexomutase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Alpha-D-phosphohexomutase, alpha/beta/alpha domain I | Alpha-D-phosphohexomutase, alpha/beta/alpha domain II | Alpha-D-phosphohexomutase, alpha/beta/alpha domain III | Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III | Alpha-D-phosphohexomutase, conserved site | Alpha-D-phosphohexomutase, C-terminal domain superfamily | Alpha-D-phosphohexomutase superfamily | Phosphoglucomutase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SXW7
|
561 |
Interactions and Pathways
No data available
Plasmids
No data available