Gene

vps4b

ID
ZDB-GENE-040426-1235
Name
vacuolar protein sorting 4 homolog B
Symbol
vps4b Nomenclature History
Previous Names
  • zgc:63682
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have ATPase activity. Involved in odontogenesis. Predicted to localize to nucleus. Is expressed in ceratobranchial 5 primary tooth; pharyngeal arch 3-7; and pharyngeal pouch. Orthologous to human VPS4B (vacuolar protein sorting 4 homolog B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Yang et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Yang et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps4b Human Ortholog
No data available
Associated With vps4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR007330 MIT domain
Domain IPR015415 Spastin/Vps4, C-terminal
Domain IPR041569 AAA ATPase, AAA+ lid domain
Domain IPR045253 Vacuolar protein sorting-associated protein 4, MIT domain
Family IPR050304 Microtubule-severing AAA ATPase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036181 MIT domain superfamily
Domain Details Per Protein
Protein Length AAA ATPase, AAA+ lid domain AAA+ ATPase domain ATPase, AAA-type, conserved site ATPase, AAA-type, core Microtubule-severing AAA ATPase MIT domain MIT domain superfamily P-loop containing nucleoside triphosphate hydrolase Spastin/Vps4, C-terminal Vacuolar protein sorting-associated protein 4, MIT domain
UniProtKB:A5WWM0 437
UniProtKB:A0A0R4IPK7 507
UniProtKB:A0A8M3AZR5 515
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vps4b-201 (1) Ensembl 2,564 nt
mRNA vps4b-202 (1) Ensembl 2,648 nt
mRNA vps4b-203 (1) Ensembl 1,640 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations