Gene
myof
- ID
- ZDB-GENE-040426-1138
- Name
- myoferlin
- Symbol
- myof Nomenclature History
- Previous Names
-
- zgc:63504 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to be involved in membrane fusion and plasma membrane organization. Predicted to localize to integral component of membrane. Used to study limb-girdle muscular dystrophy.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bonventre et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kiselev et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
limb-girdle muscular dystrophy | WT + MO1-myof | standard conditions | Kiselev et al., 2019 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000008 | C2 domain |
Domain | IPR006614 | Peroxin/Ferlin domain |
Domain | IPR012560 | Ferlin A-domain |
Domain | IPR012561 | Ferlin B-domain |
Domain | IPR012968 | FerIin domain |
Domain | IPR032362 | Ferlin, C-terminal domain |
Domain | IPR037720 | Ferlin, second C2 domain |
Domain | IPR037722 | Ferlin, third C2 domain |
Domain | IPR037723 | Ferlin, fourth C2 domain |
Domain | IPR037724 | Ferlin, fifth C2 domain |
Domain | IPR037725 | Ferlin, sixth C2 domain |
Domain | IPR037726 | Ferlin, first C2 domain |
Family | IPR037721 | Ferlin family |
Homologous_superfamily | IPR035892 | C2 domain superfamily |
Domain Details Per Protein
Protein | Length | C2 domain | C2 domain superfamily | FerIin domain | Ferlin A-domain | Ferlin B-domain | Ferlin, C-terminal domain | Ferlin family | Ferlin, fifth C2 domain | Ferlin, first C2 domain | Ferlin, fourth C2 domain | Ferlin, second C2 domain | Ferlin, sixth C2 domain | Ferlin, third C2 domain | Peroxin/Ferlin domain |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QZG1
|
2030 | ||||||||||||||
UniProtKB:A0A8M3AY58
|
2059 |
Interactions and Pathways
No data available
Plasmids
No data available