Gene
dnajb6b
- ID
- ZDB-GENE-040426-1122
- Name
- DnaJ heat shock protein family (Hsp40) member B6b
- Symbol
- dnajb6b Nomenclature History
- Previous Names
-
- dnajb6
- zgc:56709 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Involved in several processes, including myofibril assembly; negative regulation of response to endoplasmic reticulum stress; and skeletal muscle organ development. Localizes to nuclear envelope. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 1 and distal spinal muscular atrophy type 5. Is expressed in Purkinje cell; heart; lens; and solid lens vesicle. Orthologous to several human genes including DNAJB6 (DnaJ heat shock protein family (Hsp40) member B6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56709 (6 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant limb-girdle muscular dystrophy type 1 | Alliance | Muscular dystrophy, limb-girdle, autosomal dominant 1 | 603511 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chaperone J-domain superfamily | DnaJ domain | DnaJ domain, conserved site | DnaJ homolog subfamily B member 2/6-like |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B1D6
|
311 | ||||
|
UniProtKB:Q7ZW83
|
237 | ||||
|
UniProtKB:A0A8M9QGQ3
|
259 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnajb6b-201
(1)
|
Ensembl | 1,824 nt | ||
| mRNA |
dnajb6b-204
(1)
|
Ensembl | 2,898 nt | ||
| ncRNA |
dnajb6b-002
(1)
|
Ensembl | 706 nt | ||
| ncRNA |
dnajb6b-003
(1)
|
Ensembl | 694 nt |
Interactions and Pathways
No data available
Plasmids
No data available