Gene

nuf2

ID

ZDB-GENE-040426-1121

Name

UF2 component of NDC80 kinetochore complex

Symbol

nuf2 Nomenclature History

Previous Names

un-named hi2769
unm hi2769
zgc:56708

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Involved in heart development. Predicted to localize to Ndc80 complex and condensed nuclear chromosome kinetochore. Is expressed in proliferative region. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56708 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nuf2 Human Ortholog

No data available

Associated With nuf2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005549	Kinetochore protein Nuf2, N-terminal
Homologous_superfamily	IPR038275	Nuf2, N-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Kinetochore protein Nuf2, N-terminal	Nuf2, N-terminal domain superfamily
UniProtKB:Q7ZW63 InterPro	454

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nuf2-201 (1) Ensembl	Ensembl	1,567 nt	Select Tool ZFIN BLAST
mRNA	nuf2-202 (1) Ensembl	Ensembl	542 nt	Select Tool ZFIN BLAST
mRNA	nuf2-203 (1) Ensembl	Ensembl	914 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations