Gene

ptgesl

ID

ZDB-GENE-040426-1063

Name

prostaglandin E synthase 2-like

Symbol

ptgesl Nomenclature History

Previous Names

zgc:56527 (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have glutathione binding activity; heme binding activity; and lyase activity. Predicted to be involved in cell redox homeostasis and prostaglandin biosynthetic process. Predicted to localize to Golgi membrane and integral component of membrane. Is expressed in female organism; male organism; and reproductive system. Orthologous to human PTGES2 (prostaglandin E synthase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7140538 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptgesl Human Ortholog

No data available

Associated With ptgesl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR011767	Glutaredoxin active site
Domain	IPR004045	Glutathione S-transferase, N-terminal
Domain	IPR004046	Glutathione S-transferase, C-terminal
Domain	IPR010987	Glutathione S-transferase, C-terminal-like
Domain	IPR034335	Prostaglandin E synthase 2, C-terminal
Family	IPR034334	Prostaglandin E synthase 2
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily
Homologous_superfamily	IPR036282	Glutathione S-transferase, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Glutaredoxin active site	Glutathione S-transferase, C-terminal	Glutathione S-transferase, C-terminal domain superfamily	Glutathione S-transferase, C-terminal-like	Glutathione S-transferase, N-terminal	Prostaglandin E synthase 2	Prostaglandin E synthase 2, C-terminal	Thioredoxin-like superfamily
UniProtKB:A0A8M9QDX0 InterPro	237
UniProtKB:A0A8M9PR36 InterPro	233
UniProtKB:Q7ZUC7 InterPro	377

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptgesl-201 (1) Ensembl	Ensembl	1,989 nt	Select Tool ZFIN BLAST
mRNA	ptgesl-204 (1) Ensembl	Ensembl	1,475 nt	Select Tool ZFIN BLAST
ncRNA	ptgesl-002 (1) Ensembl	Ensembl	722 nt	Select Tool ZFIN BLAST
ncRNA	ptgesl-003 (1) Ensembl	Ensembl	728 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations