Gene
ptgesl
- ID
- ZDB-GENE-040426-1063
- Name
- prostaglandin E synthase 2-like
- Symbol
- ptgesl Nomenclature History
- Previous Names
-
- zgc:56527 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have glutathione binding activity; heme binding activity; and lyase activity. Predicted to be involved in cell redox homeostasis and prostaglandin biosynthetic process. Predicted to localize to Golgi membrane and integral component of membrane. Is expressed in female organism; male organism; and reproductive system. Orthologous to human PTGES2 (prostaglandin E synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140538 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR011767 | Glutaredoxin active site |
| Domain | IPR004045 | Glutathione S-transferase, N-terminal |
| Domain | IPR004046 | Glutathione S-transferase, C-terminal |
| Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
| Domain | IPR034335 | Prostaglandin E synthase 2, C-terminal |
| Family | IPR034334 | Prostaglandin E synthase 2 |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Glutaredoxin active site | Glutathione S-transferase, C-terminal | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Prostaglandin E synthase 2 | Prostaglandin E synthase 2, C-terminal | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QDX0
|
237 | ||||||||
|
UniProtKB:A0A8M9PR36
|
233 | ||||||||
|
UniProtKB:Q7ZUC7
|
377 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptgesl-201
(1)
|
Ensembl | 1,989 nt | ||
| mRNA |
ptgesl-204
(1)
|
Ensembl | 1,475 nt | ||
| ncRNA |
ptgesl-002
(1)
|
Ensembl | 722 nt | ||
| ncRNA |
ptgesl-003
(1)
|
Ensembl | 728 nt |
Interactions and Pathways
No data available
Plasmids
No data available