Gene

vrk2

ID
ZDB-GENE-040426-1046
Name
VRK serine/threonine kinase 2
Symbol
vrk2 Nomenclature History
Previous Names
  • vrk
  • zgc:56483
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in Wnt signaling pathway and peptidyl-serine phosphorylation. Predicted to localize to cytoplasm and nucleus. Orthologous to human VRK2 (VRK serine/threonine kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Umeda et al., 2022
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vrk2 Human Ortholog
No data available
Associated With vrk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Family IPR050235 Casein Kinase 1 Ser/Thr Protein Kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Casein Kinase 1 Ser/Thr Protein Kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A8M6Z1N2 486
UniProtKB:B8JHS7 574
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vrk2-201 (1) Ensembl 2,147 nt
ncRNA vrk2-002 (1) Ensembl 701 nt
ncRNA vrk2-003 (1) Ensembl 702 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations