Gene

igfbp5b

ID

ZDB-GENE-040319-2

Name

insulin-like growth factor binding protein 5b

Symbol

igfbp5b Nomenclature History

Previous Names

igfbp5
igfbp5a

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to localize to extracellular space. Is expressed in several structures, including brain; male organism; median fin fold; otic vesicle; and pectoral fin bud. Orthologous to human IGFBP5 (insulin like growth factor binding protein 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu756 (25 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With igfbp5b Human Ortholog

No data available

Associated With igfbp5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017891	Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
Domain	IPR000716	Thyroglobulin type-1
Domain	IPR000867	Insulin-like growth factor-binding protein, IGFBP
Family	IPR012213	Insulin-like growth factor binding protein 5
Family	IPR022321	Insulin-like growth factor-binding protein family 1-6, chordata
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR036857	Thyroglobulin type-1 superfamily