Gene
tlr5a
- ID
- ZDB-GENE-040219-14
- Name
- toll-like receptor 5a
- Symbol
- tlr5a Nomenclature History
- Previous Names
-
- TIR5a (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have signaling receptor activity. Involved in toll-like receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in Legionnaires' disease; cystic fibrosis; cystitis; melioidosis; and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000157 | Toll/interleukin-1 receptor homology (TIR) domain |
| Domain | IPR000483 | Cysteine-rich flanking region, C-terminal |
| Family | IPR017241 | Toll-like receptor |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Homologous_superfamily | IPR035897 | Toll/interleukin-1 receptor homology (TIR) domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
| Repeat | IPR026906 | BspA-type LRR region |
Domain Details Per Protein
| Protein | Length | BspA-type LRR region | Cysteine-rich flanking region, C-terminal | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | Toll/interleukin-1 receptor homology (TIR) domain | Toll/interleukin-1 receptor homology (TIR) domain superfamily | Toll-like receptor |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F8W4F1
|
881 |
Interactions and Pathways
No data available
Plasmids
No data available