Gene

pde7a

ID

ZDB-GENE-031222-10

Name

phosphodiesterase 7A

Symbol

pde7a Nomenclature History

Previous Names

pde7al
cb1053 (1)
wu:fk53d11
wu:fk94g02

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in signal transduction. Is expressed in several structures, including intermediate cell mass of mesoderm; mesoderm; neural crest; notochord; and tail bud. Orthologous to human PDE7A (phosphodiesterase 7A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb564 (11 images)
cb1053 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pde7a Human Ortholog

No data available

Associated With pde7a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site
Domain	IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Domain	IPR003607	HD/PDEase domain
Family	IPR023088	3'5'-cyclic nucleotide phosphodiesterase
Homologous_superfamily	IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	3'5'-cyclic nucleotide phosphodiesterase	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	3'5'-cyclic nucleotide phosphodiesterase, conserved site	HD/PDEase domain
UniProtKB:A0A8M2B9V5 InterPro	475
UniProtKB:A0A8M2B9P7 InterPro	501
UniProtKB:A0A8M2B9J0 InterPro	505
UniProtKB:A0A8M3B6M7 InterPro	463
UniProtKB:A0A8M2B9J3 InterPro	489
UniProtKB:A0A8M9PLK2 InterPro	479
UniProtKB:A0A8M9P5R9 InterPro	452
UniProtKB:A0A8M3ANI5 InterPro	490
UniProtKB:A0A8M2B9K7 InterPro	516
UniProtKB:A0A8M9PX98 InterPro	464
UniProtKB:E7FFK5 InterPro	490
UniProtKB:A0A8M3AVZ5 InterPro	504

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pde7a-201 (1) Ensembl	Ensembl	3,862 nt	Select Tool
mRNA	pde7a-202 (1) Ensembl	Ensembl	548 nt	Select Tool
mRNA	pde7a-203 (1) Ensembl	Ensembl	581 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations