Gene
supt16h
- ID
- ZDB-GENE-031118-96
- Name
- SPT16 homolog, facilitates chromatin remodeling subunit
- Symbol
- supt16h Nomenclature History
- Previous Names
-
- spt16 (1)
- fq44d08
- wu:fq44d08
- zgc:194708
- zgc:194732
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable nucleosome binding activity. Predicted to be involved in transcription elongation by RNA polymerase II. Predicted to act upstream of or within DNA replication and cellular response to DNA damage stimulus. Predicted to be located in chromosome and nucleus. Predicted to be part of FACT complex. Is expressed in dorsal aorta; hematopoietic multipotent progenitor cell; neural tube; and ventral wall of dorsal aorta. Orthologous to human SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Espanola et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Espanola et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with dysmorphic facies and thin corpus callosum | Alliance | Neurodevelopmental disorder with dysmorphic facies and thin corpus callosum | 619480 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000994 | Peptidase M24 |
| Domain | IPR013719 | Histone chaperone RTT106/FACT complex subunit SPT16-like, middle domain |
| Domain | IPR013953 | FACT complex subunit Spt16 domain |
| Domain | IPR029148 | FACT complex subunit Spt16, N-terminal lobe domain |
| Domain | IPR033825 | FACT complex subunit Spt16, peptidase M24-like domain |
| Domain | IPR048969 | FACT complex subunit SPT16, C-terminal domain |
| Family | IPR040258 | FACT complex subunit Spt16 |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029149 | Creatinase/Aminopeptidase P/Spt16, N-terminal |
| Homologous_superfamily | IPR036005 | Creatinase/aminopeptidase-like |
Domain Details Per Protein
| Protein | Length | Creatinase/aminopeptidase-like | Creatinase/Aminopeptidase P/Spt16, N-terminal | FACT complex subunit Spt16 | FACT complex subunit SPT16, C-terminal domain | FACT complex subunit Spt16 domain | FACT complex subunit Spt16, N-terminal lobe domain | FACT complex subunit Spt16, peptidase M24-like domain | Histone chaperone RTT106/FACT complex subunit SPT16-like, middle domain | Peptidase M24 | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A5A4L9
|
1033 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
supt16h-201
(1)
|
Ensembl | 8,455 nt | ||
| mRNA |
supt16h-202
(1)
|
Ensembl | 3,917 nt | ||
| mRNA |
supt16h-203
(1)
|
Ensembl | 8,455 nt | ||
| mRNA |
supt16h-204
(1)
|
Ensembl | 195 nt |
Interactions and Pathways
No data available
Plasmids
No data available