Gene
poc1b
- ID
- ZDB-GENE-031118-54
- Name
- POC1 centriolar protein B
- Symbol
- poc1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Involved in several processes, including epithelial cilium movement involved in determination of left/right asymmetry; optokinetic behavior; and retina layer formation. Predicted to localize to centriole and cytoplasm. Human ortholog(s) of this gene implicated in cone-rod dystrophy 20. Orthologous to human POC1B (POC1 centriolar protein B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63538 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cone-rod dystrophy 20 | Alliance | Cone-rod dystrophy 20 | 615973 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR050505 | WD repeat-containing protein WDR55/POC1 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat-containing protein WDR55/POC1 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z4Y7
|
409 | ||||||
|
UniProtKB:A2CEH0
|
490 | ||||||
|
UniProtKB:A0A8M3AZK7
|
486 |
Interactions and Pathways
No data available
Plasmids
No data available