Gene

tubgcp2

ID

ZDB-GENE-031118-150

Name

tubulin gamma complex component 2

Symbol

tubgcp2 Nomenclature History

Previous Names

fb81g10
wu:fb81g10
zgc:63543 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to localize to centrosome; equatorial microtubule organizing center; and gamma-tubulin small complex. Orthologous to human TUBGCP2 (tubulin gamma complex associated protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63543 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Bartoszewski et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tubgcp2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures	Alliance	Pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures	618737

Associated With tubgcp2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040457	Gamma tubulin complex component, C-terminal
Domain	IPR041470	Gamma tubulin complex component protein, N-terminal
Family	IPR007259	Gamma-tubulin complex component protein
Homologous_superfamily	IPR042241	Gamma-tubulin complex component, C-terminal domain superfamily