Gene

tob1a

ID
ZDB-GENE-031030-4
Name
transducer of ERBB2, 1a
Symbol
tob1a Nomenclature History
Previous Names
  • tob1
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have transcription corepressor activity. Involved in BMP signaling pathway and dorsal/ventral pattern formation. Localizes to cytoplasm and nucleus. Is expressed in several structures, including hatching gland; mesoderm; musculature system; nervous system; and solid lens vesicle. Orthologous to human TOB1 (transducer of ERBB2, 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Xiong et al., 2006
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tob1a Human Ortholog
No data available
Associated With tob1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002087 Anti-proliferative protein
Family IPR015676 Tob1/2
Homologous_superfamily IPR036054 BTG-like domain superfamily
Domain Details Per Protein
Protein Length Anti-proliferative protein BTG-like domain superfamily Tob1/2
UniProtKB:Q7SZR1 322
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tob1a-201 (1) Ensembl 2,279 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations