Gene
ttc21b
- ID
- ZDB-GENE-031010-34
- Name
- tetratricopeptide repeat domain 21B
- Symbol
- ttc21b Nomenclature History
- Previous Names
-
- sb:cb947
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Involved in gastrulation. Predicted to localize to intraciliary transport particle A. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 4 and nephronophthisis 12. Is expressed in Kupffer's vesicle; forerunner cell group; neural tube; and pronephric duct. Orthologous to human TTC21B (tetratricopeptide repeat domain 21B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb947 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Davis et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| asphyxiating thoracic dystrophy 4 | Alliance | Short-rib thoracic dysplasia 4 with or without polydactyly | 613819 |
| nephronophthisis 12 | Alliance | Nephronophthisis 12 | 613820 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Tetratricopeptide repeat protein 21A/21B |
|---|---|---|---|---|
|
UniProtKB:B0R0W1
|
1321 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ttc21b-201
(1)
|
Ensembl | 4,300 nt | ||
| mRNA |
ttc21b-202
(1)
|
Ensembl | 564 nt |
Interactions and Pathways
No data available
Plasmids
No data available