Gene
sh3gl1b
- ID
- ZDB-GENE-031001-6
- Name
- SH3-domain GRB2-like 1b
- Symbol
- sh3gl1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable lipid binding activity. Predicted to be involved in synaptic vesicle uncoating. Predicted to be located in early endosome membrane. Predicted to be active in glutamatergic synapse and presynapse. Is expressed in several structures, including cardiovascular system; mesoderm; musculature system; nervous system; and neural tube. Human ortholog(s) of this gene implicated in acute myeloid leukemia and high grade glioma. Orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb831 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| acute myeloid leukemia | Alliance | Leukemia, acute myeloid | 601626 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | BAR domain | Endophilin-A, SH3 domain | Endophilin/SH3RF | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IGE6
|
367 | ||||||
|
UniProtKB:A0A8M3BBQ5
|
366 | ||||||
|
UniProtKB:A0A8M2BE91
|
350 | ||||||
|
UniProtKB:Q7ZVA3
|
351 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sh3gl1b-201
(1)
|
Ensembl | 1,776 nt | ||
| mRNA |
sh3gl1b-202
(1)
|
Ensembl | 1,953 nt |
Interactions and Pathways
No data available
Plasmids
No data available