Gene

ptpn2b

ID

ZDB-GENE-030909-8

Name

protein tyrosine phosphatase non-receptor type 2b

Symbol

ptpn2b Nomenclature History

Previous Names

ptpn2
ptpn2l
cb806 (1)
wu:fc10h07
zgc:55339
zgc:76973

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Is expressed in several structures, including EVL; anterior axial hypoblast; hatching gland; mesoderm; and vasculature. Orthologous to human PTPN2 (protein tyrosine phosphatase non-receptor type 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb806 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpn2b Human Ortholog

No data available

Associated With ptpn2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Family	IPR012265	Protein-tyrosine phosphatase, non-receptor type-1/2
Family	IPR051985	Non-receptor type tyrosine-specific phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like