Gene
prdx3
- ID
- ZDB-GENE-030826-18
- Name
- peroxiredoxin 3
- Symbol
- prdx3 Nomenclature History
- Previous Names
-
- cb718 (1)
- wu:fk49e09
- zgc:110282
- zgc:112512
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have thioredoxin peroxidase activity. Predicted to be involved in cell redox homeostasis and cellular response to oxidative stress. Predicted to localize to mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; midbrain; and musculature system. Orthologous to human PRDX3 (peroxiredoxin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb718 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive spinocerebellar ataxia 32 | Alliance | Spinocerebellar ataxia, autosomal recessive 32 | 619862 |
| Corneal dystrophy, punctiform and polychromatic pre-Descemet | 619871 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000866 | Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant |
| Domain | IPR013766 | Thioredoxin domain |
| Domain | IPR019479 | Peroxiredoxin, C-terminal |
| Family | IPR050217 | Thiol-specific antioxidant peroxiredoxin |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant | Peroxiredoxin, C-terminal | Thiol-specific antioxidant peroxiredoxin | Thioredoxin domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5BJB9
|
250 |
Interactions and Pathways
No data available
Plasmids
No data available