Gene
xiap
- ID
- ZDB-GENE-030825-7
- Name
- X-linked inhibitor of apoptosis
- Symbol
- xiap Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in inhibition of cysteine-type endopeptidase activity involved in apoptotic process and positive regulation of protein ubiquitination. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to human XIAP (X-linked inhibitor of apoptosis).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked lymphoproliferative syndrome 2 | Alliance | Lymphoproliferative syndrome, X-linked, 2 | 300635 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BIR repeat | Inhibitor of Apoptosis | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|
|
UniProtKB:A2RV08
|
405 |
Interactions and Pathways
No data available
Plasmids
No data available