Gene

mxb

ID

ZDB-GENE-030721-6

Name

myxovirus (influenza) resistance B

Symbol

mxb Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have GTPase activity and microtubule binding activity. Involved in response to virus. Predicted to localize to several cellular components, including dendritic spine head; postsynaptic density; and postsynaptic endocytic zone membrane. Orthologous to human MX1 (MX dynamin like GTPase 1) and MX2 (MX dynamin like GTPase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 9 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mxb Human Ortholog

No data available

Associated With mxb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019762	Dynamin, GTPase region, conserved site
Domain	IPR000375	Dynamin stalk domain
Domain	IPR001401	Dynamin, GTPase domain
Domain	IPR003130	Dynamin GTPase effector
Domain	IPR020850	GTPase effector domain
Domain	IPR030381	Dynamin-type guanine nucleotide-binding (G) domain
Domain	IPR045063	Dynamin, N-terminal
Family	IPR022812	Dynamin
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	Dynamin	Dynamin, GTPase domain	Dynamin GTPase effector	Dynamin, GTPase region, conserved site	Dynamin, N-terminal	Dynamin stalk domain	Dynamin-type guanine nucleotide-binding (G) domain	GTPase effector domain	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:B8JKI4 InterPro	627
UniProtKB:B3DH90 InterPro	550
UniProtKB:Q800G8 InterPro	627

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mxb-201 (1) Ensembl	Ensembl	1,966 nt	Select Tool
mRNA	mxb-203 (1) Ensembl	Ensembl	1,968 nt	Select Tool
ncRNA	mxb-002 (1) Ensembl	Ensembl	1,819 nt	Select Tool
ncRNA	mxb-004 (1) Ensembl	Ensembl	321 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations