Gene

anxa11a

ID

ZDB-GENE-030707-4

Name

annexin A11a

Symbol

anxa11a Nomenclature History

Previous Names

fc09a11
sb:cb401
wu:fc09a11

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have several functions, including S100 protein binding activity; calcium-dependent protein binding activity; and phospholipid binding activity. Predicted to be involved in cytokinetic process; phagocytosis; and response to calcium ion. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 23. Is expressed in several structures, including cardiovascular system; ectoderm; integument; mesoderm; and musculature system. Orthologous to human ANXA11 (annexin A11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb401 (19 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With anxa11a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
amyotrophic lateral sclerosis type 23	Alliance	Amyotrophic lateral sclerosis 23	617839
inclusion body myopathy and brain white matter abnormalities	Alliance	Inclusion body myopathy and brain white matter abnormalities	619733

Associated With anxa11a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018252	Annexin repeat, conserved site
Family	IPR001464	Annexin
Homologous_superfamily	IPR037104	Annexin superfamily
Repeat	IPR018502	Annexin repeat

Domain Details Per Protein

Protein	Length	Annexin	Annexin repeat	Annexin repeat, conserved site	Annexin superfamily
UniProtKB:B8A4V2 InterPro	526
UniProtKB:Q7T391 InterPro	483

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	anxa11a-201 (1) Ensembl	Ensembl	2,041 nt	Select Tool
mRNA	anxa11a-202 (1) Ensembl	Ensembl	2,329 nt	Select Tool
ncRNA	anxa11a-003 (1) Ensembl	Ensembl	548 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations