Gene
ncor2
- ID
- ZDB-GENE-030616-81
- Name
- nuclear receptor corepressor 2
- Symbol
- ncor2 Nomenclature History
- Previous Names
-
- gb:be017685
- si:bz71m17.2
- smrt (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA binding activity; histone deacetylase binding activity; and transcription corepressor activity. Involved in hematopoietic stem cell differentiation; macrophage differentiation; and neutrophil differentiation. Predicted to localize to histone deacetylase complex; nuclear chromatin; and transcriptional repressor complex. Human ortholog(s) of this gene implicated in osteoarthritis. Is expressed in several structures, including anterior axial hypoblast; cardiovascular system; central nervous system; eye; and pleuroperitoneal region. Orthologous to human NCOR2 (nuclear receptor corepressor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- be017685 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Myb domain | N-CoR, GPS2-interacting domain | Nuclear receptor corepressor | SANT domain | SANT/Myb domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PQX3
|
2363 | ||||||
|
UniProtKB:E7FF48
|
2315 | ||||||
|
UniProtKB:A0A8M3B547
|
1757 | ||||||
|
UniProtKB:A0A8M3AVG1
|
2379 | ||||||
|
UniProtKB:A0A8M6YZT2
|
2353 | ||||||
|
UniProtKB:A0A8M6Z7M5
|
2341 | ||||||
|
UniProtKB:A0A8M6Z833
|
2369 |
Interactions and Pathways
No data available
Plasmids
No data available