Gene
ube2a
- ID
- ZDB-GENE-030616-72
- Name
- ubiquitin-conjugating enzyme E2A (RAD6 homolog)
- Symbol
- ube2a Nomenclature History
- Previous Names
-
- mp:zf637-2-000771
- si:bz46j2.4
- wu:fa01h11
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to localize to HULC complex and nuclear chromatin. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Nascimento type. Orthologous to human UBE2A (ubiquitin conjugating enzyme E2 A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64109 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| syndromic X-linked intellectual disability Nascimento type | Alliance | Intellectual developmental disorder, X-linked syndromic, Nascimento type | 300860 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ubiquitin-conjugating enzyme | Ubiquitin-conjugating enzyme, active site | Ubiquitin-conjugating enzyme E2 | Ubiquitin-conjugating enzyme/RWD-like |
|---|---|---|---|---|---|
|
UniProtKB:Q789K9
|
152 |
Interactions and Pathways
No data available
Plasmids
No data available