Gene
scrib
- ID
- ZDB-GENE-030616-572
- Name
- scribble planar cell polarity protein
- Symbol
- scrib Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits protein heterodimerization activity. Involved in several processes, including establishment of mitotic spindle orientation; morphogenesis of an epithelium; and nervous system development. Localizes to membrane. Predicted to colocalize with cell leading edge; ionotropic glutamate receptor complex; and synaptic membrane. Is expressed in brain and neural tube. Orthologous to human SCRIB (scribble planar cell polarity protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1089 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001478 | PDZ domain |
Family | IPR050614 | Synaptic Scaffolding LAP/MAGUK Families |
Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
Homologous_superfamily | IPR036034 | PDZ superfamily |
Repeat | IPR001611 | Leucine-rich repeat |
Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
Protein | Length | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype | PDZ domain | PDZ superfamily | Synaptic Scaffolding LAP/MAGUK Families |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9Q190
|
2010 | ||||||
UniProtKB:A0A8M9PNM8
|
2011 | ||||||
UniProtKB:A0A8M9Q197
|
1961 | ||||||
UniProtKB:A0A8M9QGP6
|
1998 | ||||||
UniProtKB:A0A8M9QBQ7
|
1900 | ||||||
UniProtKB:A0A8M9Q7L2
|
1999 | ||||||
UniProtKB:A0A8M9Q7J8
|
2047 | ||||||
UniProtKB:A0A8M9QGN8
|
2046 | ||||||
UniProtKB:A0A8M9Q7L7
|
1919 | ||||||
UniProtKB:A0A8M9QBP1
|
2031 | ||||||
UniProtKB:A0A8M9PNM3
|
2028 | ||||||
UniProtKB:A0A8M9Q1A3
|
1998 | ||||||
UniProtKB:A0A8M9PNN3
|
1974 | ||||||
UniProtKB:A0A8M9PNN8
|
1887 | ||||||
UniProtKB:Q4H4B6
|
1724 | ||||||
UniProtKB:A0A8M9Q7K5
|
2022 | ||||||
UniProtKB:A0A8M9QBP6
|
2015 | ||||||
UniProtKB:A0A8M9QBQ1
|
1986 | ||||||
UniProtKB:A0A8M9QGP9
|
1903 | ||||||
UniProtKB:A0A8M9Q183
|
2026 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
scrib-201
(1)
|
Havana | 5175 nt | |
mRNA |
scrib-202
(1)
|
Havana | 5600 nt | |
mRNA |
scrib-205
(1)
|
Havana | 674 nt | |
mRNA |
scrib-209
(1)
|
Havana | 7921 nt | |
mRNA |
scrib-210
(1)
|
Havana | 8074 nt | |
ncRNA |
scrib-002
(1)
|
Havana | 756 nt | |
ncRNA |
scrib-003
(1)
|
Havana | 736 nt | |
ncRNA |
scrib-004
(1)
|
Havana | 532 nt | |
ncRNA |
scrib-005
(1)
|
Havana | 213 nt | |
ncRNA |
scrib-006
(1)
|
Havana | 104 nt |
Interactions and Pathways
No data available
Plasmids
No data available