Gene
adat3
- ID
- ZDB-GENE-030616-531
- Name
- adenosine deaminase tRNA specific 3
- Symbol
- adat3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Predicted to localize to tRNA-specific adenosine-34 deaminase complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ADAT3 (adenosine deaminase tRNA specific 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103555 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies | Alliance | Neurodevelopmental disorder with brain abnormalities, poor growth, and dysmorphic facies | 615286 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytidine and deoxycytidylate deaminase domain | Cytidine deaminase-like |
|---|---|---|---|
|
UniProtKB:Q8JFW4
|
336 | ||
|
UniProtKB:Z4YHM2
|
336 |
Interactions and Pathways
No data available
Plasmids
No data available