Gene
abcc4
- ID
- ZDB-GENE-030616-511
- Name
- ATP binding cassette subfamily C member 4 (PEL blood group)
- Symbol
- abcc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Enables ABC-type transporter activity and efflux transmembrane transporter activity. Acts upstream of or within detoxification of inorganic compound and regulation of cilium assembly. Located in plasma membrane. Is expressed in several structures, including Kupffer's vesicle; digestive system; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1019 (12 images)
- eu668 (1 image)
- eu872 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Domain | IPR030240 | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 1 |
| Domain | IPR047083 | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 2 |
| Family | IPR009147 | Cystic fibrosis transmembrane conductance regulator |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 1 | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 2 | Cystic fibrosis transmembrane conductance regulator | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8QFL6
|
1327 |
Interactions and Pathways
No data available
Plasmids
No data available