Gene
nsfa
- ID
- ZDB-GENE-030616-37
- Name
- N-ethylmaleimide-sensitive factor a
- Symbol
- nsfa Nomenclature History
- Previous Names
-
- nsf
- si:bz18k17.1
- wu:fj33g11
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATPase activity. Involved in animal organ development; neurogenesis; and pigment granule localization. Predicted to localize to Golgi stack. Is expressed in several structures, including nervous system; neural rod; neural tube; swim bladder; and trigeminal placode. Orthologous to human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149165 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 96 | Alliance | Developmental and epileptic encephalopathy 96 | 619340 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003960 | ATPase, AAA-type, conserved site |
| Domain | IPR003338 | CDC48, N-terminal subdomain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR004201 | CDC48, domain 2 |
| Domain | IPR041569 | AAA ATPase, AAA+ lid domain |
| Domain | IPR054419 | NSF, AAA+ ATPase lid domain |
| Family | IPR039812 | Vesicle-fusing ATPase |
| Homologous_superfamily | IPR009010 | Aspartate decarboxylase-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR029067 | CDC48 domain 2-like superfamily |
Domain Details Per Protein
| Protein | Length | AAA ATPase, AAA+ lid domain | AAA+ ATPase domain | Aspartate decarboxylase-like domain superfamily | ATPase, AAA-type, conserved site | ATPase, AAA-type, core | CDC48, domain 2 | CDC48 domain 2-like superfamily | CDC48, N-terminal subdomain | NSF, AAA+ ATPase lid domain | P-loop containing nucleoside triphosphate hydrolase | Vesicle-fusing ATPase |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PEX3
|
747 | |||||||||||
|
UniProtKB:B7ZV62
|
744 |
Interactions and Pathways
No data available
Plasmids
No data available