Gene

hectd1

ID
ZDB-GENE-030616-153
Name
HECT domain containing 1
Symbol
hectd1 Nomenclature History
Previous Names
  • si:dz142b24.4
  • wu:fc30d02 (1)
  • wu:fc49f09 (1)
  • wu:fd99d04 (1)
  • zgc:123053
  • zgc:92832
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in anatomical structure development; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein K63-linked ubiquitination. Predicted to act upstream of or within protein ubiquitination. Predicted to be active in nuclear speck. Orthologous to human HECTD1 (HECT domain E3 ubiquitin protein ligase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la013098TgTransgenic insertionUnknownUnknownDNA
sa17678Allele with one point mutationUnknownSplice SiteENU
sa18554Allele with one point mutationUnknownSplice SiteENU
sa28873Allele with one point mutationUnknownSplice SiteENU
sa28874Allele with one point mutationUnknownSplice SiteENU
sa36435Allele with one point mutationUnknownSplice SiteENU
sa36436Allele with one point mutationUnknownSplice SiteENU
sa36437Allele with one point mutationUnknownPremature StopENU
sa36438Allele with one point mutationUnknownPremature StopENU
sa44875Allele with one point mutationUnknownUnknownENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With hectd1 Human Ortholog
No data available
Associated With hectd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000569 HECT domain
Domain IPR010606 Mib-herc2
Domain IPR012919 SUN domain
Domain IPR041200 FKBP3, basic tilted helix bundle domain
Family IPR045322 E3 ubiquitin-protein ligase HECTD1/TRIP12-like
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Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain superfamily Armadillo-like helical Armadillo-type fold E3 ubiquitin-protein ligase HECTD1/TRIP12-like FKBP3, basic tilted helix bundle domain Galactose-binding-like domain superfamily HECT domain HECT, E3 ligase catalytic domain Mib-herc2 Mib/herc2 domain superfamily SUN domain
UniProtKB:A0A8M3AJX0 2585
UniProtKB:A0A8M3AUD5 2523
UniProtKB:A0A0R4IGL6 2509
UniProtKB:Q8JFV5 2576
UniProtKB:A0A8M3AJX5 1334
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 17
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hectd1-201 (1) Ensembl 9,030 nt
mRNA hectd1-205 (1) Ensembl 745 nt
mRNA hectd1-206 (1) Ensembl 566 nt
mRNA hectd1-208 (1) Ensembl 8,669 nt
mRNA hectd1-209 (1) Ensembl 7,971 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHECTD114
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseHectd112
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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