Gene
gmnn
- ID
- ZDB-GENE-030429-30
- Name
- geminin DNA replication inhibitor
- Symbol
- gmnn Nomenclature History
- Previous Names
-
- sb:cb254
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Involved in Kupffer's vesicle development; cilium assembly; and determination of left/right symmetry. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 6. Is expressed in several structures, including Kupffer's vesicle; immature eye; mesoderm; nervous system; and neural tube. Orthologous to human GMNN (geminin DNA replication inhibitor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb254 (27 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Meier-Gorlin syndrome 6 | Alliance | Meier-Gorlin syndrome 6 | 616835 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR022786 | Geminin/Multicilin |
Domain Details Per Protein
| Protein | Length | Geminin/Multicilin |
|---|---|---|
|
UniProtKB:A0A8M9PAU6
|
212 | |
|
UniProtKB:Q7SXL0
|
241 |
Interactions and Pathways
No data available
Plasmids
No data available