Gene

clockb

ID

ZDB-GENE-030408-2

Name

clock circadian regulator b

Symbol

clockb Nomenclature History

Previous Names

Clock1b (1)
clock3

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Involved in circadian rhythm and photoperiodism. Predicted to localize to cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CLOCK (clock circadian regulator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With clockb Human Ortholog

No data available

Associated With clockb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Family	IPR001067	Nuclear translocator
Family	IPR047230	Circadian locomoter output cycles protein kaput-like
Homologous_superfamily	IPR035965	PAS domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily
Repeat	IPR001610	PAC motif

Domain Details Per Protein

Protein	Length	Circadian locomoter output cycles protein kaput-like	Helix-loop-helix DNA-binding domain superfamily	Myc-type, basic helix-loop-helix (bHLH) domain	Nuclear translocator	PAC motif	PAS domain	PAS domain superfamily
UniProtKB:B3DH92 InterPro	820

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	clockb-201 (1) Ensembl	Ensembl	2,947 nt	Select Tool ZFIN BLAST
mRNA	clockb-203 (1) Ensembl	Ensembl	3,297 nt	Select Tool ZFIN BLAST
ncRNA	clockb-002 (1) Ensembl	Ensembl	773 nt	Select Tool ZFIN BLAST
ncRNA	clockb-003 (1) Ensembl	Ensembl	814 nt	Select Tool ZFIN BLAST
ncRNA	clockb-004 (1) Ensembl	Ensembl	635 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations