Gene
selenon
- ID
- ZDB-GENE-030327-7
- Name
- selenoprotein N
- Symbol
- selenon Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable oxidoreductase activity. Involved in several processes, including calcium-mediated signaling; muscle cell development; and regulation of ryanodine-sensitive calcium-release channel activity. Acts upstream of or within skeletal muscle fiber development. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including anterior axial hypoblast; mesoderm; nervous system; tail bud; and trunk. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and rigid spine muscular dystrophy 1. Orthologous to human SELENON (selenoprotein N).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb686 (26 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| rigid spine muscular dystrophy 1 | Alliance | Congenital myopathy 3 with rigid spine | 602771 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Length |
|---|---|
|
UniProtKB:Q3Y4E2
|
557 |
Interactions and Pathways
No data available
Plasmids
No data available