Gene
txnrd3
- ID
- ZDB-GENE-030327-3
- Name
- thioredoxin reductase 3
- Symbol
- txnrd3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have disulfide oxidoreductase activity; electron transfer activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in cell redox homeostasis and oxidation-reduction process. Is expressed in several structures, including digestive system; hematopoietic system; nervous system; pectoral fin musculature; and ventral mesoderm. Orthologous to human TXNRD3 (thioredoxin reductase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64035 (1 image)
- cb682 (17 images)
- cb683 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR011767 | Glutaredoxin active site |
| Active_site | IPR012999 | Pyridine nucleotide-disulphide oxidoreductase, class I, active site |
| Domain | IPR002109 | Glutaredoxin |
| Domain | IPR004099 | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain |
| Domain | IPR011899 | Glutaredoxin, eukaryotic/virial |
| Domain | IPR023753 | FAD/NAD(P)-binding domain |
| Family | IPR001100 | Pyridine nucleotide-disulphide oxidoreductase, class I |
| Family | IPR006338 | Thioredoxin/glutathione reductase selenoprotein |
| Family | IPR046952 | Glutathione reductase/thioredoxin reductase-like |
| Homologous_superfamily | IPR016156 | FAD/NAD-linked reductase, dimerisation domain superfamily |
| Homologous_superfamily | IPR036188 | FAD/NAD(P)-binding domain superfamily |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | FAD/NAD-linked reductase, dimerisation domain superfamily | FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain superfamily | Glutaredoxin | Glutaredoxin active site | Glutaredoxin, eukaryotic/virial | Glutathione reductase/thioredoxin reductase-like | Pyridine nucleotide-disulphide oxidoreductase, class I | Pyridine nucleotide-disulphide oxidoreductase, class I, active site | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Thioredoxin/glutathione reductase selenoprotein | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1PCD1
|
602 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
txnrd3-201
(1)
|
Ensembl | 3,116 nt | ||
| mRNA |
txnrd3-202
(1)
|
Ensembl | 1,803 nt |
Interactions and Pathways
No data available
Plasmids
No data available