Gene
prdx2
- ID
- ZDB-GENE-030326-2
- Name
- peroxiredoxin 2
- Symbol
- prdx2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have thioredoxin peroxidase activity. Predicted to be involved in several processes, including cell redox homeostasis; hydrogen peroxide catabolic process; and removal of superoxide radicals. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Is expressed in several structures, including digestive system; nervous system; neural tube; presumptive blood; and ventral mesoderm. Orthologous to several human genes including PRDX2 (peroxiredoxin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb58 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000866 | Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant |
| Domain | IPR013766 | Thioredoxin domain |
| Domain | IPR019479 | Peroxiredoxin, C-terminal |
| Family | IPR024706 | Peroxiredoxin, AhpC-type |
| Family | IPR050217 | Thiol-specific antioxidant peroxiredoxin |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant | Peroxiredoxin, AhpC-type | Peroxiredoxin, C-terminal | Thiol-specific antioxidant peroxiredoxin | Thioredoxin domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DGJ6
|
197 |
Interactions and Pathways
No data available
Plasmids
No data available