Gene

p2rx8

ID

ZDB-GENE-030319-7

Name

purinergic receptor P2X, ligand-gated ion channel, 8

Symbol

p2rx8 Nomenclature History

Previous Names

P2X.514 (1)
zP2X5.2 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Exhibits extracellularly ATP-gated cation channel activity. Involved in cation transport. Predicted to localize to integral component of nuclear inner membrane. Is expressed in Rohon-Beard neurons; cranial ganglion; hypothalamus; lateral hypothalamic nucleus; and trigeminal ganglion.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Appelbaum et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With p2rx8 Human Ortholog

No data available

Associated With p2rx8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR001429	P2X purinoreceptor
Homologous_superfamily	IPR027309	P2X purinoreceptor extracellular domain superfamily

Domain Details Per Protein

Protein	Length	P2X purinoreceptor	P2X purinoreceptor extracellular domain superfamily
UniProtKB:Q7SZM1 InterPro	390

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	p2rx8-201 (1) Ensembl	Ensembl		1,217 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations