Gene

p2rx2

ID
ZDB-GENE-030319-2
Name
purinergic receptor P2X, ligand-gated ion channel, 2
Symbol
p2rx2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits extracellularly ATP-gated cation channel activity. Involved in ion transport. Predicted to localize to integral component of nuclear inner membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 41. Is expressed in Rohon-Beard neurons and cranial ganglion. Orthologous to human P2RX2 (purinergic receptor P2X 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Appelbaum et al., 2007
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With p2rx2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 41 Alliance Deafness, autosomal dominant 41 608224
Associated With p2rx2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001429 P2X purinoreceptor
Family IPR003045 P2X2 purinoceptor
Homologous_superfamily IPR027309 P2X purinoreceptor extracellular domain superfamily
Domain Details Per Protein
Protein Length P2X2 purinoceptor P2X purinoreceptor P2X purinoreceptor extracellular domain superfamily
UniProtKB:Q7SZL9 400
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA p2rx2-201 (1) Ensembl 1,292 nt
mRNA p2rx2-202 (1) Ensembl 3,557 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations