Gene
skp2
- ID
- ZDB-GENE-030219-158
- Name
- S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
- Symbol
- skp2 Nomenclature History
- Previous Names
-
- id:ibd5121
- sb:cb933
- wu:fa10b08
- wu:fj97b11
- zgc:162950
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in G2/M transition of mitotic cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; and regulation of cell cycle. Predicted to localize to SCF ubiquitin ligase complex; cytosol; and nucleus. Human ortholog(s) of this gene implicated in prostate carcinoma. Is expressed in several structures, including alar plate midbrain region; digestive system; intermediate cell mass of mesoderm; nervous system; and ventral mesoderm. Orthologous to human SKP2 (S-phase kinase associated protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb933 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | F-box domain | F-box-like domain superfamily | Leucine-rich repeat, cysteine-containing subtype | Leucine-rich repeat domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A3KP53
|
410 | ||||
|
UniProtKB:A0A8M2B860
|
427 |
Interactions and Pathways
No data available
Plasmids
No data available