Gene
cpox
- ID
- ZDB-GENE-030131-9884
- Name
- coproporphyrinogen oxidase
- Symbol
- cpox Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable coproporphyrinogen oxidase activity. Acts upstream of or within hemoglobin biosynthetic process. Predicted to be located in membrane. Predicted to be active in mitochondrial intermembrane space. Is expressed in hematopoietic system; mesoderm; presumptive blood; and ventral mesenchyme. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb535 (6 images)
- IMAGE:7156501 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary coproporphyria | Alliance | Coproporphyria | 121300 |
| Harderoporphyria | 618892 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Coproporphyrinogen III oxidase, aerobic | Coproporphyrinogen III oxidase, conserved site | Oxygen-dependent coproporphyrinogen III oxidase superfamily |
|---|---|---|---|---|
|
UniProtKB:Q05AK3
|
449 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available