Gene

eif1

ID
ZDB-GENE-030131-956
Name
eukaryotic translation initiation factor 1
Symbol
eif1 Nomenclature History
Previous Names
  • eif1b (1)
  • gc20 (1)
  • wu:fb54a12
  • wu:fb64g08
  • wu:fk63g02
  • zgc:85781 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have ribosomal small subunit binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to localize to eukaryotic 43S preinitiation complex. Orthologous to several human genes including EIF1 (eukaryotic translation initiation factor 1).
Genome Resources
Note
In July 2019 it was determined that this gene, formerly known as eif1b, is actually an ortholog of mammalian EIF1 and the name was changed accordingly. Nomenclature changes can be confusing, so it is done only after compelling evidence is found to support the change. In this case, the evidence included strong AA identity, synteny and phylogenetic analysis. Another gene has been identifed as orthologous to the mammalian EIF1B.
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif1 Human Ortholog
No data available
Associated With eif1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001950 SUI1 domain
Family IPR005874 Eukaryotic translation initiation factor SUI1
Homologous_superfamily IPR036877 SUI1 domain superfamily
Domain Details Per Protein
Protein Length Eukaryotic translation initiation factor SUI1 SUI1 domain SUI1 domain superfamily
UniProtKB:Q7ZUI8 113
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA eif1b-001 (1) Ensembl 1,336 nt
ncRNA eif1b-002 (1) Ensembl 773 nt
ncRNA eif1b-003 (1) Ensembl 940 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations